The city's old Hotel de los Inmgrantes, or Immigrants' Hotel, functioned until 1951. More than a million immigrants, mainly from Europe but also from Africa and Asia, stayed here free of charge on their arrival in the city by ship. The museum is managed by the Universidad Nacional de Tres de Febrero (UNTREF).
Exhibits display the different stages in the process of immigration: the journey, the arrival, integration, and legacy, through historic documents, photographs, films, contemporary testimonies and objects from the past. One of the most noted parts of the collection are the registration books with the details of all the immigrants who entered the country.
There have also been installations from travelling artists including Carlos Trilick, Graciela Sacco, Gabriela Golder, Mariano Sardón and Annemarie Heinrich.